There are numerous types of cancer cell lines available for research, representing various types and subtypes of cancer. Here are some examples of commonly studied cancer cell lines:
- HeLa (Cervical Cancer): HeLa cells are one of the most widely used and well-known cancer cell lines. They were derived from a cervical cancer patient named Henrietta Lacks in the early 1950s.
- MCF-7 (Breast Cancer): MCF-7 cells were derived from a metastatic breast adenocarcinoma. They are commonly used to study breast cancer biology, hormone receptor signaling, and drug sensitivity.
- A549 (Lung Cancer): A549 cells are derived from a lung carcinoma. They are frequently used to study lung cancer biology, drug resistance, and respiratory diseases.
- PC-3 (Prostate Cancer): PC-3 cells are derived from a bone metastasis of prostate adenocarcinoma. They are commonly used to study prostate cancer progression, metastasis, and therapeutic interventions.
- HT-29 (Colon Cancer): HT-29 cells were derived from a human colorectal adenocarcinoma. They are extensively used to study colorectal cancer biology, drug responses, and epithelial cell differentiation.
- U87 (Brain Cancer): U87 cells were derived from a human glioblastoma multiforme, a highly malignant brain tumor. They are widely used in brain cancer research, including studies on tumor invasion, angiogenesis, and therapeutic interventions.
- Jurkat (Leukemia): Jurkat cells are derived from a patient with acute T-cell leukemia. They are commonly used to study leukemia biology, immune responses, and drug screening.
- SK-MEL-28 (Melanoma): SK-MEL-28 cells were derived from a malignant melanoma. They are frequently used to study melanoma progression, metastasis, and melanocyte biology.
These are just a few examples, and there are many other cancer cell lines available for different types of cancers. Each cell line has its own unique characteristics, molecular profile, and behavior, making them suitable for studying specific aspects of cancer biology and therapeutic interventions.